Madara Uchiha

Madara Uchiha is one of the main antagonists of Naruto Shippudden, he was one of the 1st members of Uchiha Clan.

Story
Madara was the legendary leader of the Uchiha clan. He founded Konohagakure alongside his rival, Hashirama Senju, with the intention of beginning an era of peace. When the two couldn't agree on how to achieve that peace, they fought for control of the village, a conflict which ended in Madara's death. Madara, however, rewrote his death and went into hiding to work on his own plans. Unable to complete it in his natural life, he entrusted his knowledge and plans to Obito Uchiha shortly before his actual death. Years later, Madara would be revived, only to see his plans foiled before his final death.

Naruto Games Appearances
Naruto Shippuden: Clash of Ninja Revolution 4

Madara is one of the playable characters.

Naruto Shippuden: Ultimate Ninja Storm 5

He returns as a playable character.

Crossover Appearances
2K10 Anime Battle Coliseum

He appears as a playable character facing Naruto franchise alongside Boruto Uzumaki, he is also one of the bosses of the game alongside Dezrath, Zamasu, Dio and Altair.

Anime Fighting Jam

Madara is part of the Naruto Shippuden Universe.

Anime Fighting Jam II: Berserk=Age

Madara returns to be playable.

Arena of Sagas

Madara is part of the roster alongside Naruto Uzumaki, Sasuke Uchiha, Kakashi Hakate and Itachi Uchiha.

Shonen Jump Warriors

Madara is part of Naruto cast.

Shonen Jump VS. Capcom: Fight of Century

Madara is part of the Shonen Jump cast.

Super Smash Bros. 5: Legends

He is an unlockable character.

Heroes Infinity

Madara is an unlockable character.

Trivia

 * "Madara" (斑) can be translated as "spots" or "speckles".
 * Despite Madara being a user of the Six Paths Senjutsu and using various senjutsu techniques, he is not listed as a user of senjutsu in the fourth databook.