The Powerpuff Girls: Chemical X Crusade

the Powerpuff Girls: Chemical X Crusade is a videogame by Activision and Cartoon Network that continues the events of the 1998 Powerpuff Girls series.

Chemical X Crusade
Blossom, Bubbles and Buttercup find a team of opposite powerpuffs named "the Bizarropuff Girls". When Townzarrosville (A bizarro Townsville that the PPG's sent the BPG's to) is harvested by Zooper, Boogie Man and Tritorus, the Powerpuff Girls (with their friends) must ally with the Bizzaropuffs and save their town and the Powerpuffs' town before the energy harvest and the Xtrokkon (a chemical that creates powerful beings to fight the PPGs) takes full effect. the Powerpuffs also find other 'puffs from different worlds as well.

Rise of Puffkind's Greatest
Blossom, Bubbles, Buttercup, Bunny, Bullet, Boat, Brylee, Buddy and Bumblebee fight to save a digital world beyond Townsville and cyberspace from a more powered up force of evil, with Axton, the Rowdyruff Boys and Bat helping along the way.

Playable

 * Blossom (Cathy Cavadini) - The pink leader of the PPG's.
 * Bubbles (Tara Strong) - The cheerful blue girl of the PPG's.
 * Buttercup (E.G. Daily) - The tough green girl of the PPG's.
 * Brick (Rob Paulsen) - The red leader of the Rowdyruff Boys. (unlockable)
 * Boomer (Rob Paulsen) - The blue member of the Rowdyruff Boys. (unlockable)
 * Butch (Roger L. Jackson) - The green member of the Rowdyruff Boys. (unlockable)
 * Princess Morbucks (unlockable)
 * Boat (OC) (Annick Obonsawin) - The aqua mermaid Powerpuff girl.
 * Blissful (OC) - The yellow protector of the Powerpuff girls.
 * Bliss (2K16) (unlockable)
 * Bumblebee (OC) - The grass green Irish Powerpuff girl.
 * Brunch (OC) (Ashley Taylor) (unlockable) - The big gold Powerpuff girl who eats a lot.
 * Berserk - The red leader/vocalist of the Powerpunk girls. (unlockable)
 * Brat - The blue rocker of the Powerpunk girls. (unlockable)
 * Brute - The green drummer of the Powerpunk girls. (unlockable)
 * Bruise (OC) - The red stressed fighter of the Powerpuffs. (unlockable)
 * Bunny - The purple happy-go-lucky Powerpuff girl who is recreated with stable ingredients this time. (unlockable)
 * Bullet - The orange powerpuff squirrel. (unlockable)
 * Bell (Mae Whitman) (kind-of-OC) - The shy, but optimistic silver Powerpuff girl. (bigger missions)
 * Brylee - The yellow rowdyruff boy with lightning powers. Originally by PowerpuffRowdyruff45. (unlockable)
 * Buddy - The orange rowdyruff boy that teams up with Brylee. Originally by RLedd. (unlockable, bigger missions)
 * Gabe - The powerpuff-rowdyruff hybird who is best buds with Butch. Originally by gabelovesbutch, who is deactivated. (unlockable)
 * Bombard (OC) - The green mutant powerpuff who is a quick-learning bounty hunter. (unlockable)
 * Blozarro (Cathy Cavadini) (OC) - The pink clueless leader of the Bizarropuff Girls.
 * Bubblzarro (Denise Oliver) (OC) - The gloomy blue girl of the Bizarropuffs.
 * Bizarrercup (Stacey DePass) (OC) - The cowardly green girl of the Bizzaropuffs.
 * Dynamo - A robot used to fight bigger monsters for the PPG's. (bigger missions)
 * PowerProf. Utonium (Tom Kane) (unlockable)
 * Kid Cosmic - The kid who wears the stone of telekinesis as hero powers. (unlockable)
 * Regina (OC) - Kid Cosmic's friend who wears the stones of shields and teleportation. (unlockable)
 * Stacy Stickler (Ashley Taylor) - A stick figure with the power to break the laws of physics. (Stickin' Around) (DLC (Cross X Crusade))
 * Edgar and Eva - Two twins that have the power of Zimmerization that 13 gave to them. (Zimmer Twins) (DLC (Cross X Crusade))
 * Henry - A mischievous boy that pulls pranks on everyone he knows. (Horrid Henry) (DLC (Cross X Crusade))
 * Emelia - A living doll who makes wisecracks and tricks no human had done. (Sitio do Picapau Amarelo) (DLC (Cross X Crusade))
 * Inez (Annick Obonsawin) - a Latin-American smarty-pants girl with excellent vocabulary and is part of the cybersquad. (Cyberchase) (DLC (Cross X Crusade))
 * Zooper (OC) - A powerpuff that Zach created using Chemical X, leftover parts of destroyed Zackbots, knowledge of the Kratt brothers and everything related to a usual teenager. (unlockable)
 * Axton - A digital being who comes to give hints, tips, tricks and helpful items to the player when it's facing harder missions. Originally by PowerpuffRowdyruff45. (DLC (Rise of Puffkind's Greatest))
 * Bat - The purple rowdyruff who is really good at baseball and is best buds with Brick. Originally by KaylaTechHeart. (DLC (Rise of Puffkind's Greatest))

Non-playable

 * Mojo Jojo (Roger L. Jackson)
 * Red Nose Mojo Jojo (Red Nose Zone) (DLC (FREE Red Nose Day))
 * Ms. Bellum
 * the Mayor of Townsville (Tom Kenny)
 * Red Nose Mayor of Townsville (Red Nose Zone) (DLC (FREE Red Nose Day))
 * Zippy - A friendly Zubo.
 * Allegro - The panda from Painbow.
 * HIM (Tom Kane) - An overlord bent on defeating the Powerpuff Girls.
 * Fuzzy Lumpkins
 * Red Nose Fuzzy Lumpkins (Red Nose Zone) (DLC (FREE Red Nose Day))
 * the Amoeba Boys
 * Ms. Keane
 * Gangreen Gang
 * Lucita and Little Pete (Sitio do Picapau Amarelo) (DLC (Cross X Crusade))

Bosses

 * Mojodome - a Technodrone-looking spider robot.
 * Princess Morbucks
 * King Painbow (OC) - A giant sentient rainbow sent by Allegro, set out to mess with the 2K16 girls.
 * Mojo Jojo (Chemical X'd) - A powered-up Mojo Jojo that first appeared in The Powerpuff Girls Movie.
 * Doctor Nefarious (Tom Kenny) - A cyborg commander that uses energy to strengthen his defenses and attacks.
 * TBA.
 * Boogie Man (Kevin Richardson)
 * Tritorus (OC) - A volcanic space titan that is responsible for harvesting Townzarrosville and the Xtrokkon.
 * CyberRuckus - The mutant cybervirus creature from Cyberchase: Twisted Space. (DLC (Cross X Crusade))

Costumes

 * Blossom (Dance Pantsed) (unlockable)
 * Blossom (2K16)
 * Blossom (ROTPPG) (unlockable)
 * Blossom/Liberty Belle (Super Zeroes) (unlockable)
 * Attorney Blossom (unlockable)
 * Blossom (Run of the Mill Girls) (unlockable)
 * Blossom (Beta ROTPPG) (unlockable)
 * Robot Blossom (Dance Pantsed) (DLC (Vol. 1))
 * Rockstar Blossom (DLC (Vol. 2))
 * Red Nose Blossom (Red Nose Day) (DLC (FREE Red Nose Day))
 * Bubbles (Dance Pantsed) (unlockable)
 * Bubbles (2K16)
 * Bubbles (ROTPPG) (unlockable)
 * Bubbles/Harmony Bunny (Super Zeroes) (unlockable)
 * Bubbles (Run of the Mill Girls) (unlockable)
 * Bubbles (Beta ROTPPG) (unlockable)
 * Mojo Jojo Bubbles (unlockable)
 * Robot Bubbles (Dance Pantsed) (DLC (Vol. 1))
 * Red Nose Bubbles (Red Nose Day) (DLC (FREE Red Nose Day))
 * Buttercup (Dance Pantsed) (unlockable)
 * Buttercup (2K16)
 * Buttercup (ROTPPG) (unlockable)
 * Buttercup/Mange (Super Zeroes) (unlockable)
 * Matrix Buttercup (unlockable)
 * Buttercup (Run of the Mill Girls) (unlockable)
 * Buttercup (Beta ROTPPG) (unlockable)
 * Robot Buttercup (Dance Pantsed) (DLC (Vol. 1))
 * Prof. Buttercup (Criss Cross Crisis) (DLC (Vol. 1))
 * Red Nose Buttercup (Red Nose Day (DLC (FREE Red Nose Day))
 * Old Bunny (Twisted Sister (unlockable)
 * Maid Brick (unlockable)

Production
After greenlighting three more seasons of the '98 Powerpuff Girls show for an older audience after the sixth season, there is an announcement that this game (originally titled "the Powerpuff Girls: the Advent of the Samurai") is coming to the Wii, Playstation 2, Playstation 3, PSP and Nintendo DS. It was supposed to be a samurai game where the Powerpuff Girls are fighting against Samurai Mojo. More info coming soon.

Trivia

 * TBA